-
How to Read a VCF File: A Practical Guide to Variant Call Format
Learn what every part of a VCF file means: header lines, the eight fixed columns, genotypes like 0/1, special alleles, common mistakes and a reproducible bcftools check.
Latest guides
All articles-
AlphaGenome Atlas Explained: What Its 9 Billion Variant Predictions Mean
AlphaGenome Atlas predicts effects of every possible single-letter DNA change. See what its AVI scores help researchers prioritize, and what…
-
GRCh37 vs GRCh38 vs T2T-CHM13: Choosing a Human Reference Genome
Compare GRCh37, GRCh38, T2T-CHM13 and the human pangenome, understand reference-build mismatches, and choose compatible files for reproducible NGS analysis.
-
FASTQ and Phred Quality Scores: A Practical NGS QC Guide
Understand FASTQ records, Phred Q20/Q30 scores, ASCII encoding, quality-score binning, and a reproducible FastQC/MultiQC checklist before NGS alignment.
-
PCR Primer Design Around a Genomic Variant: A Practical Checklist
PCR primer design around a genomic variant: a practical checklist for choosing the assembly, transcript and sequencing primers, then checking…
-
How Human DNA Works: A Complete Guide to Chromosomes, Genes, and Genomes
How human DNA works, explained simply: how DNA, genes and chromosomes fit together in the human genome, how genes are…
-
Human Vs AI: A Historic Victory at the AtCoder World Tour Finals 2025
In a thrilling showdown that captivated the programming community worldwide, Polish coder Przemysław Dębiak, known by his handle “Psyho,” narrowly…
-
The Hidden Toll of Sleep Disruption in Cancer Survivorship
Did you know that cancer survivors are two to three times more likely to suffer from chronic sleep disturbances than…
-
How Nutrition Shapes Our Cells to Fight Cancer
Did you know that up to 50% of cancer cases worldwide could be prevented through targeted nutrition and lifestyle changes?…
-
Can Rare Diseases Affect Anyone? Myths vs. Facts
Rare diseases affect millions of people across the globe, yet they often remain misunderstood. Their name suggests infrequency, but the…
Software for laboratories
Run your genomics lab on Genomics LIMS
Track every sample from accession to signed report, on a PostgreSQL database your lab controls.
Written by a working genomics researcher
Sci Chores is run by Taimoor Khan, a bioinformatician at the Advanced Center for Genomic Technologies, Khyber Medical University, Peshawar. The guides, tools and software come out of real sequencing and rare-disease work.
- 28
- rare-disease exome cases analysed in one year
- 272
- families in a major exome cohort contribution
- 50+
- researchers, clinicians and students trained